Sex cord—gonadal stromal tumour is a group of tumors derived from the stromal component of the ovary and testis , which comprises the granulosa , thecal cells and fibrocytes. In contrast, the epithelial cells originate from the outer epithelial lining surrounding the gonad while the germ cell tumors arise from the precursor cells of the gametes, hence the name germ cell. Their diagnosis is histological: only a biopsy of the tumour can make an exact diagnosis. They are often suspected of being malignant prior to operation, being solid ovarian tumours that tend to occur most commonly in post menopausal women. This group of tumours is significantly less common than testicular germ cell tumours in men,  and slightly less common than ovarian germ cell tumours in women see Ovarian cancer. These tumours are of the following types, characterized by their abnormal production of otherwise apparently normal cells or tissues.
Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists
Sex cord-stromal ovarian tumours and steroid cell tumours | Target Ovarian Cancer
We offer a widget that you can add to your website to let users look up cancer-related terms. Menu Contact Dictionary Search. What Is Cancer? Cancer Statistics. Cancer Disparities. Cancer Causes and Prevention.
Sex cord-stromal ovarian tumours and steroid cell tumours
This histopathologic ovarian tumor group differs considerably from the more prevalent epithelial ovarian tumors. Although sex cord-stromal tumors present in a broad age group, the majority tend to present as a low-grade disease that usually follows a nonaggressive clinical course in younger patients. Furthermore, because the constituent cells of these tumors are engaged in ovarian steroid hormone production e. The World Health Organization sex cord-stromal tumor classification has recently been revised, and currently these tumors have been regrouped into the following clinicopathologic entities: pure stromal tumors, pure sex cord tumors, and mixed sex cord-stromal tumors. Moreover, some entities considered in the former classification e.
There are different types of ovarian sex cord stromal tumours SCSTs. These can be non cancerous benign or cancerous malignant. Granulosa cell tumours are the most common type. Treatment depends on several factors including your age, the type of tumour, and how advanced it is the stage. Most women are diagnosed at an early stage and treatment usually works well.